ȫҽҩbIȺ
A Global Biomedical Industry Cluster
һbIBȦ
22
2025-10
114|Ԫ_ˎ_ȫԺ
1022գBioBAYҵŴҩذȫսԺκƷIBI363 (PD-1/IL-2-bias)IBI343 (CLDN18.2 ADC)ԼһзĿIBI3001 (EGFR/B7H3 ADC)ѡȨ Ŵｫ12Ԫ1ԪսԹȨͶʣԼDẔܽ߿ɴ114ԪͬʱŴﻹ۷ֳɡ ݺŴҩȫΧڹͬһIOʯƷ IBI363 (PD-1/IL-2-bias)ͬҵҩڹͬЭͬһµĿƻعͬʱŴҩIBI363ڳлҵȨ档ŴҩIBI343 (CLDN18.2 ADC)ڴлĶȨ档⣬ŴҩIBI3001 (EGFR/B7H3 ADC)ڴлȨĶѡȨ Ŵｫ12ԪϹʽõ1ԪսԹ ȨͶʣϹ۽ϽӹɷݷЭǰʮյĹɷݼȨƽ м20%ŴȨúϼ߿ɴ102ԪDẔ κܽ߿ɴ114ԪŴﻹÿѡҩڴлDZ۷ֳɣIBI363г˫ʧģʽ IBI363һPD-1/IL-2-bias˫ԿںϵףͬʱPD-1/PD-L1ͨ·IL-2ͨ·оIBI363ͨƫԼIL-2˼·ѡCD8+ TϸϸɱЧʵͬʱ붾صTϸչֳڴͳIL-2ҩİȫԡ 2025ٴѧᣨASCOṫ1b/2ٴʾIBI363ҩΰ֫/ĤͺɫԼȶͣMSSֱ УչֳӦ档ĿǰIBI363ѽעٴһIOҩ״СϸΰsqNSCLCȫ3עٴоδӦ֢ѻйҩƷල֣NMPAͻƷּFDAͨʸFTD Ŵҩͬƽһµٴƻ̽IBI363ΪIOʯƷٴDZĿǰѻ۵ij1200ߵʵٴݣ˫ƽIBI363ڷСϸΰNSCLCֱCRCȫչһNSCLCһCRCӦ֢⣬˫ƻڽIBI363Ӧ֢ٴ IBI343һͰCLDN18.2칹ø1TOPO1ƼADCٴʾİȫ˹ЧźšĿǰIBI343йձչθ/θʳܽ紦3ٴоG-HOPE-001Ӧ֢ѻйNMPAͻƷ֣ͬʱIBI343ԼܹƵٵٰPDACȫ1/2ٴоɣӦ֢ѻNMPAͻƷּFDA FTD Э飬ŴｫҩIBI343ڴлȫҿҵȨ档ҩصչIBI343ȫһθһٰ Դ˴ȨҩŴ֧DẔ߿ɴʮٷֱȵĸλݶ۷ֳɡ01EGFR/B7H3 ADCȫҵȨѡȨ IBI3001һ1ٴεİB7-H3EGFR˫ADC߱ؿƣǿEGFRá鵼ڻãԼǿЧADC鵼ϸԣٴǰģչֳ߰ȫƴڡ Э飬ŴｫҩIBI3001ڴлȫҿҵȨѡȨҩʹȨŴ֧ȨѡDẔ߿ɴʮٷֱȵλݶ۷ֳɡ ŴϯзܻԲʿ dzҩɴ˴ξ̱ȫսԺһIOADCҩĿȫƸִ±ҪƾŴIOADCרҵͷḻۣҩȫҵǿʵ˫ͨЭͬһµٴƻٽŴһƷȫг츣ȫߣʵֲƷֵ⣬˴κҲŴȫսͼĹؼһչȫ֣ʵ֡ɳΪһҩҵijԶĿꡣ ҩȫҵܲ Teresa Bitetti ǶŴɴ˴սԺܡŴһIOADCӵѧרҵۺзʵIBI363IBI343һҩȫʵĹؼհףΪߴϣŴȡõٴչDZܹ裬ڴͨ˫ͷЩĿDZͬʱȫзʵҵƶЩҩݼȫߡIBI363IBI343Ϊߴ߸ͻƣ2030DZ
鿴20
2025-10
ż2800Ԫ B+ ʣٴзƽ̨չ
գBioBAYҵżBridGene Biosciences, Inc.¼ BridGeneڽ2800 ԪB+ʡɿʱͶؼͶʡǴͶԼͶʷͶʺȴͶͬ롣 ʽҪƽ˾ĺѡҩBGC-515 ٴBGC-515 һʵĹ TEAD ƼĿǰIٴƻڽ II ٴо⣬ʽƶ˾ڶĿ 2027 ٴΣٹ˾ĺ߲֡ ͬʱҲһǿBridGeneսԺƶзIMTAC?(Isobaric Mass-Tagged Affinity Characterization)ѧѧƽ̨ѧѧѧĹ㷺ӦDZ BridGene Biosciences ϴʼ˼ϯִйٲƽʿPing Cao, Ph.D.ʾΪ˾ṩ˹ؼԴԼƽĿBGC-515ٴ II ڿһʲָ֧ѳҩеĿٴΣҲͨսԺչ IMTAC? ƽ̨Ӧñ߽磬ѧתΪ츣ߵĴƷ ʱϻԾDZʾǷdzܹͶ BridGene Biosciences ʡBridGene IMTAC? ƽ̨һǿҲ컯ҩģʽʹ˾ܹΪɳҩİеСҩԹ TEAD Ƽ BGC-515 ΪĹ߲ƽԼĿߵչ BridGene ߱ΪߴƷҽҩ쳤ڼֵľDZ BridGene BiosciencesBridGene Biosciences һҴƼ˾ڷֺͿͳɳҩеСҩ˾з IMTAC?Isobaric Mass-Tagged Affinity Characterizationѧѧƽ̨ڻϸɸѡСȫĽϣʶͽλ㣬Ӷ־иٴֵĺѡҩӡĿǰBridGene ӵжԪзߣ BGC-515 һʵչٴоĹ TEAD Ƽǹ˾ٴεĺѡҩ֤ IMTAC? ƽ̨ڡѳҩе㷢ϵǿиƽ̨˾ѲֶĴĿBridGene ѧѧתҽѧϣµ·ΪȫߴԵĴƷ ڿʱͶʹ˾2019꣬һרҵ˽ļȨͶʹʱΪȫΨһͶƽ̨пǿIJҵרעҽҩĹȨͶʡʱͨصIJҵӽǣעȫȵҩзƽ̨Ƽ˾ҽе˾ȣڳΪѧҵʱŦijں顣 ڸؼͶ2001ؼͶڳҵҵͶʡͶģʽרעҽƽҵͶʣսԹȨͶΪVCPEPre-IPOȫͶʽΡӵйΪȾ۽ҽƽרҵͶŶӣڳΪȫӰҽƽͶʻʲģ230ԪңȺͶҽƽҵ110ңƶҽơӰҽơ41ҵɹС˾ҵйȫڡϺ۵ȵؽӪģȫΧͶҽƽҵΪȫʱҽҵطչ»Эҵ߳ɾΰҵ ڱǴͶǴͶйȵҽƿƼͶʻ֧ҼԪרעƶȫҵֵͻԴ¡ĿǰͶʳ70ҵ30ƽ̨˾Ǹ߶ҽе＼ѧʵ60+ȫ״Ʒͻơ40+֤80%Ʒȫ֡ԡȫ渳+սϡΪսԣȴ̬йҽȫֵˡ ȴͶȴͶ2012רעϢѧ˹ܼ༼ǰؿƼڷͶʡĿǰʲģ30ԪңۼͶʹС֪50ҵǼҵоͳЭͬΪǵԸ̽½
鿴15
2025-10
ָٰ BioBAYҵûҩFDAٴ
գBioBAYҵûҽҩɷ˾³ơûзĺԴСӶҩYH-Z-02ʽFDAٴɣӦ֢ΪٰһͻԽչ־йҩڹˡ֢֮˹ؼһ PART 01 ƾ֡ԴȻҩչֿתƾDZ ٰ֢֮һָ߶ȶԵϵͳ5ʲ10%ٰϸϮǿpתƣϸԭԵͣЧӦϸϡ٣ɰԤķӰе㲻ԣԤޡYH-Z-02һԴںСӽǰǣٴǰоչֳĿ˫عЧԭãϣٰϸΡԡΡȶתƷֳDZ YH-Z-02ͨеЭͬûʵЧͨøЧϮѪͨٽTFPIͷţϸƤϸãתγɣԵP-ѡأϸ-ѪСۼγɣת·ֶе;ģʽʹYH-Z-02ڿתչֳصơ оʾYH-Z-02ܹTϸܣǿTCR-TϸK-RASͻٰϸʶΪӦTCR-Tϸṩ˿ԡ PART02 ˶ݣΰȫ ҩṹĸԺͼܵԴԻʵĸŵԣΘһȸߡԺҲԴԻʸŵһֱҵشսûɹ˸ȩpԣȶYH-Z-02ڶѪ֯ƷŨȵΪĿ˳ƽṩҪ֧ţҲΪҩṩµ˼· ˽⣬ʳзظҩУYH-Z-02൱ߵļʾİȫԡδ۲쵽ضԷӦһоʾҩﱾԽİȫԣΪٴתṩ˰ȫԱϡ ûﴴʼ˼涭³ʾ ûΪBiobayפҵ֮һԳʼռسģרעڴȻҩƷзΪȫߴͻԵƷYH-Z-02ƷٴĻûһҪ̱ҲȻҩзһشͻơFDAʷϣȻҩƷһֱΪYH-Z-02ijɹչʾԺʹԣҲûԭʵ֡һɾ͵ȡãҽƶҩȻҩչ߷ıϡ֪̺žҽҩDZYH-Z-02Ʒһϸijɹǽд¡רҵεYH-Z-02ٴоȡսгΪȫṩȫЧѡͬʱҲ̽ຣҩȻҩзᣬΪƶȫҽҩ¹ û ûҽҩɷ˾ԴȻҩзΪĿƼҵȻ²ƷĿҵ˾ӵݹҵƼ˲ҵݹҵҵҩƼ켼ҹоݷġҸ¼ҵʡ˾зƷȺöҼƼĿ֧֣ҿƼСҵ»𣬹ʮһ塢ʮ塰شҩơƼشר⣬ؼװר⣬ԼʡмƼĿ֧֡ҵĿǰй߲ƷΪȻƷйΪֿѹȻƷMental Zen齺ң2022гôС
鿴14
2025-10
ʡُBioBAY@2ϰ
գʡ2025ӪҵǿϵаBioBAYҵŴѡ2025Ӫҵ200ǿһ2025ӪҵзͶ100ҡУŴʢǽС Ŵ ΰŴ״ӪҵǿͳŴӪΪ938054ԪвƷIJϷذ²ƷŴӪռֵˮǴߣֵһͻ1500ԪΪ۹ʱгҽҩͷҵҲΪ˹ҩĵ䷶ 14ŴĿǰ16ƷС꣬״۲IGF-1RȵУЧTED60ҩõĿհףTEDƵٴ6µףŴIJƷȫGCG/GLP-1˫мҩ˶ĻУݺͨԤ⣬˶20252026۶ֱﵽ6Ԫ18ԪΪŴҵĺ ڻҵ+˫֡£ʱгŴﳤ6£ʷо棬Ŵ202520262027Ԥϵ114Ԫ142Ԫ179ԪӪѡУŴδһΡ ڡ2025ӪҵзͶ100ҡУŴ߾ȫʡڰλŴ2025H1ƱʾϰзͶ9ԪĿǰгʮ¹ƽȫٴУܹעıASCOϴʵһȫ״IOƷIBI363ʧܡPD-L1ͱͻݣչֳ˫˫ѼͳĶơ ʢ ѡ2025ӪҵзͶ100ҡʢǺҽҩȫӹ˾ʢڼҵͬĿǰʢаHER2ͻNSCLCߵйзADC鵥ά?עÿ鵥?鵥עҺﾲ?6ƷС ҵ棬ʢͶʽ20ԪɹȵijģҵأԭҺӦܹ滮10ܴﵽ800֧ͬʱͨ£ͻƹؼռΪг˹Ҹ߶ԶַӦ䣬310000L26000LﷴӦߣעÿ鵥10000LﷴӦ20247»С
鿴10
2025-10
4.13|ԪAviadoBiobAAVr
գBioBAYҵŽUgeneX TherapeuticsAviadoBioǩһЭ飬˫ŴѧUGX-202ĿҵɶѡȨЭ顣AviadoBio ȨѡôлUGX202ĤɫرԣRPӦ֢ĿҵȨȫɡʹѡȨŽʸøߴ4.13ԪԤз̱̱Լ۶Ȩʹ÷ѡ Ž20217£ܲλݹҵBioBAYɸҩ»ʱۿƼҩ﹫˾˾۽ۿƼڻƲƷԸйϸԼԼרеĹŴѧԭλתֻзŴѧAAVƲƷ Ž˹ŴѧԼAAV忪ƽ̨йߣһIITٴ飬ѹڽʾİȫԺЧ UGX-202 ˴ΣŽȨUGX-202һٴεزAAVƷĤɫرԣRPߣڶδӦ֢ٴΡUGX-202ŽһŴѧвƷAAVΪ壬ؿжȵĴ¹ףԸȾĤϸйܣؽڸйϸԼӾͨ·UGX-202Ϊͻġͨ͡»Ʒͻ˺ƣڶȺĤɫرԡStargardtĤ֢ڸػư߲ȡUGX-202¿ǡԼӵתŻʵͬѵٴ֡ AviadoBioŸ壬AviadoBioϯִйLisa DeschampsزɷֱԣŴѧһ˷ܵٴ UGX-202 һȻпܸĤߵ ͼƬԴAviadoBio ŽܲʿҲʾκ˫UGX-202δٴDZгǰĸ߶ģͬʱҲǹ˾гҪ̱ŽŶӵĹҰзʵԼߵȫֵ ȥ꣬ƷȫΧһȳ AAVزΪĻƷƾ辫ĵDZڵġһЧѸٳΪȫҽѧоĿǰȫ 9 AAV ĻҩУѪѲSMA ȶӦ֢йѳΪȫ AAV ƷзԾĹ֮һݿӦȫƽ̨ġ2025 ȫа Top 50ʾйлڻĿʵѧӰԾȫڶ BioBAYӿֳһҵŽ⣬ŵֽвAAVƷѿAAVƷڿٲ컯·Biotechҵͨзʺȫгҵհס
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